Cochrane Database Syst Rev, (11):CD011015, 20 Nov 2015 Cited by: 1 article | PMID: 26588711 | PMCID: PMC6885032. BACKGROUND Although superficial thrombophlebitis of the upper extremity represents a frequent complication of intravenous catheters inserted into the peripheral veins of the forearm or hand, no consensus exists on the optimal management of this condition in clinical practice. Thrombolysis for treatment of acute deep vein thrombosis. See the CKS topics on NSAIDs - prescribing issues and Analgesia - mild-to-moderate pain for prescribing information. The best treatment for these blood clots in the hands and arms remains unclear. Authors' conclusions: No study evaluated the effects of ice or the application of cold or hot bandages. Comparison 5 Topical treatment versus active control: transdermal nitroglycerine versus heparinoid gel, Outcome 6 Adverse events. Would you like email updates of new search results? 2007 Apr 18;(2):CD004982. ... subcutaneously once daily for 7 days is more effective than Ibuprofen given orally three times daily for 7 days for the treatment of superficial thrombophlebitis (STP). Unable to load your collection due to an error, Unable to load your delegates due to an error, Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included studies, Risk of bias summary: review authors' judgements about each risk of bias item for each included study. NEW GUIDELINES for Management of Superficial Vein Thrombosis In May 2015, new UWMedicine Guidelines for Management of Superficial Vein Thrombosis were approved. Authors: Di Nisio M, Peinemann F, Porreca E, Rutjes AW We extracted data on methodological quality, patient characteristics, interventions and outcomes, including improvement of signs and symptoms as the primary effectiveness outcome, and number of participants experiencing side effects of the study treatments as the primary safety outcome. Diagnosis of SVT A pilot randomized double-blind comparison of a low-molecular-weight heparin, a nonsteroidal anti-inflammatory agent, and placebo in the treatment of superficial vein thrombosis. No. FOIA Reporting on safety data was limited, with no available information on some treatments (notoginseny creams, parenteral low-molecular-weight heparin or defibrotide). 2012 Mar 14;(3):CD004982. We could not analyse data on primary outcomes together because the trials examined different treatments, in different ways, looking at different outcomes. Overall, the risk of bias in individual trials was moderate to high, although poor reporting hampered a full appreciation of the risk in most studies. Di Nisio M, Peinemann F, Porreca E, Rutjes AWS, Di Nisio M, Peinemann F, Porreca E, Rutjes AWS. Superficial venous thrombosis is a blood clot in a superficial vein of the upper or lower extremities or, less commonly, in one or more veins of the chest or breast (Mondor disease). Author information: (1)Department of Medical, Oral, and Biotechnological Sciences, Università "G. D'Annunzio" of Chieti-Pescara, Chieti, Italy2Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands. Superficial thrombophlebitis is different to, and much less serious than, deep vein thrombosis (DVT). the treatment of acute infusion superficial thrombophlebitis is limited and of low quality, and we do not have enough information to recommend the use of any of the treatments studied. 2018 Feb 25;2(2):CD004982. This is the third update of a review first published in 2007. FP: none known EP: none known AWSR: none known, Risk of bias graph: review authors' judgements about each risk of bias item…, Risk of bias summary: review authors' judgements about each risk of bias item…, Comparison 1 Topical treatment versus inactive control: heparin gel versus placebo, Outcome 1…, Comparison 1 Topical treatment versus inactive control: heparin gel versus placebo, Outcome 2…, Comparison 1 Topical treatment versus inactive control: heparin gel versus placebo, Outcome 3…, Comparison 1 Topical treatment versus inactive control: heparin gel versus placebo, Outcome 4…, Comparison 1 Topical treatment versus inactive control: heparin gel versus placebo, Outcome 5…, Comparison 2 Topical treatment versus inactive control: Essaven gel versus placebo, Outcome 1…, Comparison 2 Topical treatment versus inactive control: Essaven gel versus placebo, Outcome 2…, Comparison 3 Topical treatment versus inactive control: Phlebolan versus placebo, Outcome 1 Clinical…, Comparison 3 Topical treatment versus inactive control: Phlebolan versus placebo, Outcome 2 Adverse…, Comparison 4 Topical or oral treatment versus inactive control: topical or oral diclofenac…, Comparison 5 Topical treatment versus active control: transdermal nitroglycerine versus heparinoid gel, Outcome…, Comparison 6 Topical treatment versus active control: notoginseny cream versus heparinoid cream, Outcome…, Comparison 7 Topical treatment versus active control: topical versus oral diclofenac, Outcome 1…, Comparison 7 Topical treatment versus active control: topical versus oral diclofenac, Outcome 2…, Comparison 7 Topical treatment versus active control: topical versus oral diclofenac, Outcome 3…, Comparison 7 Topical treatment versus active control: topical versus oral diclofenac, Outcome 4…, Comparison 7 Topical treatment versus active control: topical versus oral diclofenac, Outcome 5…, Comparison 7 Topical treatment versus active control: topical versus oral diclofenac, Outcome 6…, National Library of Medicine The … › The most common site of UEDVT involves the axillary and subclavian veins; however, the more distal brachi… doi: 10.1002/14651858.CD004982.pub6. Comparison 7 Topical treatment versus active control: topical versus oral diclofenac, Outcome 3 Pain reduction. Warfarin initiation nomograms of 5 mg and 10 mg for venous thromboembolism. 2003;163(14):1657-1663. Cochrane Database Syst Rev. The condition usually improves on its own.Your doctor might also recommend these treatments for both types of thrombophlebitis: 1. Accessibility In short, the evidence about the treatment of acute infusion superficial thrombophlebitis is limited and of low quality, and we do not have enough information to recommend the use of any of the treatments studied. Superficial venous thrombosis in the upper extremity most commonly results from IV infusions or catheterization; varicose veins seem to be the main risk factor for the lower extremity, especially among women. Comparison 1 Topical treatment versus inactive control: heparin gel versus placebo, Outcome 5 Local adverse events. No study evaluated the effects of ice or the application of cold or hot bandages. The blood clot usually clears and the inflammation dies down within a few weeks. Thrombosis of superficial veins has long been regarded as a benign disorder. But, if you are at risk of developing a DVT or have problems that affect the way your blood clots, you will likely need to take anticoagulation medication. FP received no internal or external funding. LMWH (e.g. Thrombophlebitis is a disease of the circulatory system. BACKGROUND Description of the condition Superficial thrombophlebitis of the upper extremity is a relatively Search methods: Sex. Blood-thinning medications. Comparison 5 Topical treatment versus active control: transdermal nitroglycerine versus heparinoid gel, Outcome 3 Time (h) to halving of erythema. Study with 15 participants assessed anything other than localised control of the lower.. And several other advanced features are temporarily unavailable an array of Topical,. 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